Methicillin resistance & inducible clindamycin resistance in Staphylococcus aureus

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Methicillin resistance & inducible clindamycin resistance in Staphylococcus aureus

BACKGROUND & OBJECTIVES Methicillin resistant Staphylococcus aureus (MRSA) isolates with inducible clindamycin resistance (iCR) are resistant to erythromycin and sensitive to clindamycin on routine testing and inducible clindamycin resistance can only be identified by D-test. This study was aimed to detect methicillin resistance and iCR among S. aureus isolates, effectiveness of some commonly u...

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Inducible clindamycin resistance among Staphylococcus aureus isolates

Introduction: Clindamycin is considered an useful alternate drug in penicillin-allergic patients in the treatment of skin & soft tissue infections caused by Staphylococcus aureus. Staphylococcus spp. can be resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but may appear susceptible to clin...

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Failure of clindamycin treatment of methicillin-resistant Staphylococcus aureus expressing inducible clindamycin resistance in vitro.

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Inducible Clindamycin Resistance in Staphylococcus aureus Isolated from Clinical Samples

Increasing frequency of methicillin resistant Staphylococcus aureus (MRSA) infections and changing patterns in antimicrobial resistance have led to renewed interest in the use of macrolide-lincosamide-streptogramin (MLS) antibiotics to treat such infections. Inducible macrolides, lincosamides, type B streptogramins (MLS(Bi)) resistance has to be identified to avoid clinical failure of clindamyc...

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Inducible clindamycin resistance in clinical isolates of Staphylococcus aureus.

Background: Staphylococcus aureus is one of the most important agents causing nosocomial infections. Inducible clindamycin resistance is an important concern, because common laboratory tests could not detect it. Objectives: The aim of this study was to detect the inducible clindamycin resistance by D-test method. Materials and Methods: A total of 209 clinical S. aureus isolates were collected a...

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ژورنال

عنوان ژورنال: Indian Journal of Medical Research

سال: 2016

ISSN: 0971-5916

DOI: 10.4103/0971-5916.182628